COVID-19 Pandemic Reaches Highest Daily Increase in Cases

On Sunday, June 21, WHO Director-General Dr. Tedros Adhanom Ghebreyesus called COVID-19 “the challenge and opportunity of our time” as the pandemic reaches a new phase. The world appears to be caught in the first wave of the pandemic, with cases still increasing daily. Countries reported 183,000 new cases on June 21, marking the largest daily increase since the emergence of the virus in 2019.

Growing cases

Brazil appears to be the worst-hit country currently. Its government’s much-criticized COVID-19 response led to a disastrous 55,000 new cases to add to its caseload of one million patients. Brazil has reported 49,976 COVID-19-related deaths. Brazilians took to the streets to protest President Jair Bolsanaro, as he appeared to bolster support of the military as tensions mount in the capital, Brasilia.

On the African continent, recorded cases reached 306,567 according to the Africa Centres for Disease Control and Prevention. The African CDC also reported 146,212 recoveries amid a total death toll of 8,115 as the continent’s disparate regions face different phases of the epidemic. North African countries have achieved relative success through strict containment measures, keeping the total regional caseload at around 81,500.

In Southern Africa several nations are still facing the initial wave of infections with 101,700 recorded cases while West Africa has seen 62,400, East Africa reported 31,400, and Central Africa recorded 29,500. Africa’s young population appears to be keeping death tolls relatively low but, like in many places across the world, much remains unclear about the scale of unreported cases.

Socioeconomic impact

While Africa’s youthful population might be more resilient against the virus, the socioeconomic consequences of the global crisis are prompting a renewed call for solidarity in the pandemic’s aftermath. The president of Costa Rica, Carlos Alvarado Quesada, joined forces with Ghebreyesus to launch a “Solidarity Call to Action.”

Only by working together, the statement says, can we ensure a fair and equitable response to the economic aftermath of the crisis. The WHO’s June 1 call to action urges governments to avoid international competition over vaccines and economic support in order to mitigate the long-term effects of the pandemic that has claimed almost half a million lives in less than a year.

Urging an “open and collaborative” approach

Governments and researchers should “promote innovation, remove barriers, and facilitate open sharing of knowledge, intellectual property and data,” according to a WHO statement, as international frictions have emerged over the distribution of an eventual COVID-19 vaccine.

The WHO hopes to encourage a spirit of “open and collaborative approaches” to ensure an “equitable distribution and access to products needed for COVID-19.”

Some commercial companies working on vaccines are pressuring governments to outbid each other to receive “first access” to an eventual vaccine.

The US and EU are already buying up hundreds of millions of doses of yet unproven drugs, causing many to many fear the crisis will further exacerbate global inequalities.

Desperate need for unity

Calls for the development of a “People’s Vaccine” through global cooperation appear to have resulted in little, despite the concept’s broad support by many current and former world leaders.

The new “Solidarity Call to Action” appears to attempt to refocus the global pharmaceutical industry and its government funders to prioritize global stability and a common humanity over political decisions that lead to competition over vaccine access.

The Call to Action has received formal support from a variety of WHO member states across the world, but the future will tell if any true collaboration will materialize.

“The world is in desperate need of national unity and global solidarity. The politicization of the pandemic has exacerbated it,” Dr Tedros said on Monday, June 22, “…the greatest threat we face now is not the virus itself, it’s the lack of global solidarity and global leadership.”

Saudi Arabia Shakes off COVID-19 Curfew

After months of strict COVID-19 curbs, there is finally light at the end of the tunnel for residents of Saudi Arabia. As promised on May 26, the nationwide coronavirus curfew was lifted at 6 a.m. on Sunday, June 21, and the country’s commerce and sporting venues are reopening. 

It appears that, even though Saudi Arabia is looking towards a “new normal,” some restrictions will remain in place for the foreseeable future. Mandatory face masks and social distancing will remain, as will the ban on international travel and the Umrah pilgrimage until further notice.  

As of Sunday, commercial and economic activity will be allowed to restart, “provided utmost caution and protection are taken, as well as observance of full abidance by the precautionary measures and preventive procedures,” an official statement carried by state news outlet the Saudi Press Agency said on June 20. At present, gatherings cannot exceed 50 people, which may limit some workplaces and activities.  

On Saturday, in another piece of good news for Saudi Arabia’s business sector and workers, the Ministry of Human Resources and  Social Development said that workplaces can increase attendance to 75% starting June 29. In the meantime, the public sector is encouraged to continue to operate on a flexible timetable and facilitate “teleworking” for remote workers.     

Sports lovers across the country also rejoiced on Saturday when the Ministry of Sports announced Saudi Arabia’s sports centers and halls can reopen from June 21. Sports facilities must observe a number of COVID-19 control measures including equipment sterilization, providing hand sanitizer, enforcing social distancing, and encouraging patrons to bring and use their own equipment where possible. 

Handshakes and physical contact between athletes also remain off-limits under the Ministry of Sports guide. Contact sports like taekwondo and karate will have to wait a little longer before they can recommence tournaments, while spectators and audiences remain banned from all sporting events. 

As restrictions ease further, the Ministry of Interior reiterated its calls for all residents to download the country’s tracking and COVID-19 advice application. The new freedoms also came with a reminder that any workplace or individual violating precautionary measures will be prosecuted accordingly. 

On Saturday, the Ministry of Health reported 740 new infections, taking Saudi Arabia’s total number of confirmed COVID-19 cases to 154,233, including 1,230 fatalities and 98,917 recoveries. 

Read also: Saudi Arabia to Expand Library Network

50,000 COVID-19 Cases in Egypt Amid Plans to Restart Tourism

On Friday, June 19, Egypt passed the unfortunate milestone of recording more than 50,000 cases nationwide. The government reported 1,218 new cases on Thursday, June 18, after the country saw its largest daily increase yet when 1,677 cases and 62 deaths hit headlines on June 13. According to data reported to the World Health Organization (WHO) Egypt now has 50,437 cases and 1,938 deaths, with no sign of a flattening curve in infection rates.

Growing Epidemic

As the most populous country in the Middle East and North Africa, Egypt would logically record more cases than its smaller neighbors, but the continuous increase in cases is worrying experts. The Egyptian Medical Syndicate on Tuesday, June 16 reported that 68 Egyptian doctors have died of the coronavirus and 430 have contracted the virus, making up roughly 5-7% of all doctors.

According to Anadolu Agency, unofficial sources have claimed that a further 1,000 healthcare workers have caught the virus, leading to 180 deaths by Tuesday, June 16. At the end of May, the Guardian revealed that one of its reporters in Egypt, Ruth Michaelson, was forced to leave the country after reporting on a study that disputed Egypt’s official tally.

While Egypt initially designated a number of COVID-19 isolation hospitals for every citizen that showed even mild symptoms. The continual increase in new cases appears to have pushed the health ministry to now offer prescriptions that are delivered to patients’ homes as Egypt’s healthcare system struggles to cope with an influx in new cases.

Reopening tourism

On the same day that Egyptian health officials released news of the unfortunate new milestone, the Egyptian Minister of Tourism and Antiquities, Khaled al-Anany struck an altogether more positive tone. In an interview with Chinese outlet Xinhua, al-Anany stated that Egypt is “gearing up” to welcome foreign tourists.

Anany stated that Egypt “will reopen its airports and resorts in the provinces of Red Sea, South Sinai, and Matrouh to international tourists in an attempt to ease the anticipated recession on the tourism sector due to COVID-19 spread.” The three provinces where tourism will be allowed are all coastal provinces, where Egyptian officials have reported relatively low numbers of coronavirus infections.

“I have received official requests to resume tourist flows from Italy and Ukraine,” Anany told Xinhua, but tempered expectations by saying “we are not expecting a high number of tourists for the time being, not only in Egypt, but the whole world.”

Egypt’s reliance on income from its important tourism sector could force it to risk a premature reopening. Tourism in Egypt brought in $13 billion in 2019, which was an all-time record for the country.

Preventative measures

Several tourism-dependent countries around the world have offered a range of coronavirus-related measures to assuage potential tourists’ worries. The Cypriot Ministry of Tourism announced that any tourist that tests positive for COVID-19 infection on arrival in Cyprus will be provided with free treatment and no hotel expenses on the island. Campsites and hotels around Europe are also reopening as many countries slowly lift lockdowns.

The global pandemic has created an unprecedented situation for tourism around the Mediterranean as millions of Europeans will have had their original travel plans canceled and could soon be shopping for bargains. Meanwhile, traditional tourist destinations compete to offer visitors a safe way to enjoy the hot summer months.

For Egypt, this means improving hygiene standards and introducing a variety of preventative measures. “We are not in a hurry because we give priority to the safety of tourists as well as preserving our image as a tourist destination,” Tourism Minister Anany told Xinhua: Safety has become the new focus in international tourism.

“Hotels have ramped up hygiene, archaeological sites have been sanitized and beaches cleaned up,” Anany stated as Egypt’s seeks to reassure visitors. Whether Egypt’s ambitions toward restarting its vital tourism sector amid a growing epidemic will be successful remains to be seen.

For the many Egyptians who work in the industry, it is clear they would rather listen to their tourism minister’s optimism than despair over the increased numbers of infections reported by health officials.

Subject of Tunisian COVID-19 Scandal Details Quarantine ‘Escape’

No sooner had Tunisian Prime Minister Elyes Fakfakh said the country had beaten COVID-19, than a scandal broke involving one woman who “escaped” quarantine over the weekend and went on to attend a wedding.  

The woman has since come forward and told local radio she left the state-sanctioned quarantine hotel because of a name mix-up. The young lady, who asked to stay anonymous for fear of backlash, said she was in the center after finally being repatriated from what was meant to be a quick trip to Canada, but turned into a three month ordeal because of COVID-19. 

After petitioning the Tunisian Embassy in Canada, the woman who normally resides in Menzel Temime was finally able to secure a seat on a repatriation flight alongside her sister. Early on the morning of Sunday, June 7, the pair’s flight from Montreal touched down in Tunisia. They were temperature tested and sent to a quarantine center in Yasmine Hammamet, where they both spent seven days in confinement.  

“Anarchy” at Quarantine Hotel  

On the eighth day of quarantine, and still asymptomatic, the woman left the COVID-19 hotel believing she had been cleared by authorities.  

“At the reception, there was a lot of anarchy, no-one knew what to do — to stay or to go,” she told local radio station Sabra FM.

“A few hours earlier, they knocked on the doors of our rooms and told us to take our luggage downstairs to the reception, and that we could leave.  

“Confused, we spent a long time waiting in the reception, from 5pm to 11pm. During that entire time, no one told us anything. On the contrary, the tension was so high that fights began to break out,” she explained.   

After leaving she visited her parents and attended a family wedding in Menzel Temime — where 80 people who came into contact with her are now in mandatory isolation, according to TAP News.  

After the ceremony, the young lady received a phone call from the quarantine facility telling her to return. It now appears that it was her sister, who has the same family name, that was actually authorized to leave.   

“When they began to announce the names of those who could leave quarantine, I heard my surname. I thought they meant me, but in fact it was my sister. It was my fault for not checking the name properly,” she said.

“I still have no documentation to say that I have tested positive. I had been there for a whole week, and received not a single document to say that I was positive. No one said that there was a positive case either. Logically, if you have a positive case, you would think they would have left them in their room. That was not the case.” 

The young lady felt the need to come forward and tell her side of the story, given the abuse she has endured and the rumors flying about the incident. “Do you think I’m that reckless?” she told the radio host. 

Media reports said the woman ate at a restaurant with her fiancé after leaving the COVID-19 hotel and infected a number of police officers before returning to the facilities — allegations she denies. 

Tunisian Blunders 

On June 18, another story emerged that another young person — this time a 24-year-old man repatriated from Kuwait, had been wrongly given permission to leave quarantine despite testing positive for COVID-19. The man arrived back in Tunisia on June 9 and had been under mandatory quarantine in a hotel until he was released on Tuesday, before receiving his test results.  

The Ksour Essef resident’s test came back positive, and he has now been transferred to a COVID-19 treatment center in Monastir. Health authorities are now busily tracing and testing his family and friends.  

The poor handling of these two cases has raised serious doubts about the Tunisian government’s handling of the COVID-19 pandemic and thrown into question its de-confinement strategy. 

On Sunday, June 14, the virus seemed to be under control. Prime Minister Elyes Fakhfakh made what now appears to be a premature declaration of victory against COVID-19. After the announcement, cases spiked on June 16 and 17.  

Nevertheless, Tunisia’s COVID-19 case load remains low compared with its neighbors. There are only 1,128 total confirmed cases and 50 deaths, and just 74 of those cases remain active.  

Despite warnings from Health Minister Abdellatif Mekki about a second wave of the virus, Tunisia is still on track to become the first North African country to reopen all borders on June 27.

Read also: Tunisia Eyes Economy After Declaring COVID-19 Victory

Rich Countries Seek Priority Access to COVID-19 Vaccine

In order for an eventual COVID-19 vaccine to save as many lives as possible, it would require rapid distribution, and to those countries struggling with the highest infection rates. The chances that will happen are slim, say several experts who see an increasingly competitive race for first-access to a potential vaccine.

“We have this beautiful picture of everyone getting the vaccine, but there is no road map on how to do it,” the Associated Press was told by Yuan Qiong Hu, a senior legal and policy adviser at Doctors Without Borders in Geneva.

Hu predicts that the existing structure, in which companies establish patents at every step of vaccine development, will hamper the distribution and development of a vaccine that could be made available to all. “We can’t afford to face these multiple layers of private rights to create a ‘people’s vaccine,’” she told the AP.

Three phases

Several possible vaccines are under development across the world thanks to global efforts, with around a dozen in the early stages of testing. Vaccine development requires any potential remedy to go through a three-phase process that tests the efficacy of the drug while ensuring that side effects do not pose unforeseen risks.

In the first phase, small groups of people receive the trial vaccine. If the vaccine proves successful without any significant health risks among the participants, the process moves to the second phase.

In phase two, the clinical study expands to a group of people who are part of the risk group for whom the vaccine is intended, which in COVID-19 cases would be older people and those vulnerable because of pre-existing illnesses.

The third and final phase tests the vaccine on thousands of people to ensure safety and a proven efficacy to avoid false positives and detect possible allergic reactions or side effects.

Private investment

Several wealthy countries have spent millions to support the rapid development of possible vaccine candidates and ensure a potential vaccine could be manufactured on a large scale. In exchange for these investments, these countries are expected to receive vaccines before others.

The British government has declared that the first 30 million doses of a possible vaccine under development at Oxford University will be earmarked for British citizens. The US became entangled in a diplomatic row with France over the potential future distribution of a French vaccine candidate to which the US expected first access because of its investments.

AstraZeneca, a drug manufacturer that intends to produce Oxford University’s vaccine, has signed an agreement with the US that would guarantee 300 million doses for the US, to be delivered as soon as possible.

The same manufacturer struck a deal with four EU countries to also supply them with 300 million doses. Drug manufacturers appear to be actively goading governments into making early commitments to buy yet-unproven drugs, playing countries against each other as they stand to make giant profits.

While pharmaceutical companies have pledged to provide a not-for-profit version of their vaccines, it is becoming clear that the world’s richest will be the first to receive the vaccines, even if other countries need them much more. Another example of the perverse nature of privatized medicine, it will be the richest, not the sickest, who will receive priority in this global crisis.

MENA Region Faces Wave of Post-Lockdown Protests

Citizens of several countries in the Middle East and North Africa (MENA) have taken to the streets following the easing of COVID-19 measures. Citizens are demanding action from their governments after having adhered to painful lockdowns and curfews that brought severe economic hardship.

In Lebanon, Iraq, Syria, and Tunisia, large protests have emerged over the last week as citizens call upon government officials to ease their suffering. While COVID-19 fears begin to wane, a new focus on structural poverty and inefficient government is emerging across the region as protesters express their discontent.

Lebanon

The Lebanese military arrested dozens of protesters on Monday, June 15, for alleged acts of vandalism. Protesters expressed their frustration with skyrocketing inflation amid a spiraling currency crisis, while the indebted nation struggles to balance its debt obligations with popular demands for a significant increase in living conditions.

After nearly two months of empty streets, economic deprivation, and fear of the coronavirus, the Lebanese people have returned to the streets to protest the lack of solutions offered by the government of Hassan Diab. Banks and shops were attacked as Lebanese people grow more desperate, even as new sanctions on neighboring country Syria are likely to further damage Lebanon’s economy.

Iraq

Newly inaugurated prime minister Mustafa al-Kadhimi’s “honeymoon phase” in government has ended quickly as increasing austerity measures are sparking furious protests. Monthly pensions were hit by a drop in oil-revenue that is forcing the government to take unpopular measures. Nearly one million Iraqis depend on their pension each month and this month the $920 pension was more than $100 short, according to France24.

The Iraqi government has introduced several ambitious reform plans, but a dramatic fall in government revenue as a result of cratered oil prices and production cuts has meant introducing painful cuts to public sector salaries and pensions. Public sector employment has served as a method to appease Iraqis since the 2003 US invasion, but falling state oil revenues have now undermined this strategy.

Syria

Syria has seen few large protests since the 2011 pro-democracy protests that started a civil war. But protests again emerged over the rise in prices of basic necessities, a doubling in food prices and continued corruption in government. The city of Druze saw four days of intense protests as the Syrian Pound continues to fall dramatically in value.

The protesters are unlikely to see a swift resolution to their concerns as the “Caesar Act,” a new round of US sanctions targeting Syria, is set to heavily impact the last remaining economic activity that has sustained the country’s flailing economy. With an apparent consolidation of power ongoing in Damascus that has gone public, Bashar al-Assad’s regime is facing renewed pressure from all sides.

Tunisia

Protests have emerged in at least seven Tunisian cities, Reuters reported on Thursday, June 18. Unemployed and economically deprived people across the country protested what they considered government inaction in the face of a continued economic crisis. University graduates shouted “we need jobs” in Gafsa and hundreds protested in Hajeb el Ayoun and Sidi Bouzid.

The Tunisian tourism sector has suffered an unprecedented crisis after COVID-19 measures closed borders and shut the industry that provides 10% of state revenue. After a decade of high inflation and unemployment, Tunisians now call for an increased focus on jobs by protesting and even halting the country’s phosphate production through sit-ins.

A new era

The current protests across the MENA-region are likely only the beginning of popular unrest in the region, with global institutes like the IMF predicting that local economies will suffer from post-lockdown economic woes for some time to come. Protests against corruption and ineffective government appear to be supported by data, and the World Bank has called for greater transparency from MENA-governments.

As global oil prices continue to be volatile, supported by painful production cuts, revenue will likely remain impacted in many oil-dependent MENA-countries. With structural economic issues in many countries, unemployment and poverty are likely to worsen in the months ahead, as the region braces itself for a new era of popular discontent.

Fate of Oil Markets Relies on COVID-19 Containment

Oil prices dipped again on Wednesday, June 17, as Arizona, Florida, and Texas reported record numbers of new COVID-19 cases. Many conservative states have seen an uptick in infections during their drive towards a rapid reopening of local economies with insufficient adherence to containment measures.

The worrying numbers caused oil prices to fall. Brent crude dropped $0.38, 0.9% of the total value, while American WTI oil fell $0.56 or 1.5% of its value. Oil markets had been optimistic over growing demand amid reopening economies, discounting the possibility of a second wave.

But US infectious disease expert Anthony Fauci on June 16 stated that the United States had not yet left its first “wave.” “When I look at the TV and I see pictures of people congregating at bars when the location they are indicates they shouldn’t be doing that, that’s very risky,” Fauci said in an interview with the Wall Street Journal.

Second wave

Countries like Tunisia and New Zealand had initially declared themselves coronavirus-free before having to revise expectations after detecting new local infections.

“We think the oil market is not currently pricing in a significant probability of either second waves of coronavirus cases in key consumers and the associated lockdowns, or anything less than a rapid return to economic business-as-usual,” analysts of Standard Chartered told Reuters.

In the midst of a stock market fueled by stimulus spending, in which bankruptcies have been essentially made impossible, oil markets are enjoying less of an artificial boost. The only methods that have helped alleviate prices somewhat are painful production cuts and the closing of wells.

OPEC

The Organization of the Petroleum Exporting Countries (OPEC) released its monthly report on June 17, predicting a gradual recovery in global demand for oil. OPEC credited much of its production cuts to the recent slight recovery in oil prices.

“The oil market was strongly supported by a reduction of the global crude oil surplus, thanks mainly to the historic voluntary production adjustment agreement,” OPEC stated in its report, released the same day participants in the OPEC+ production cuts are set to meet to review the impact of the move.

Although OPEC is cautiously optimistic, it still predicts that global oil demand will drop by 6.4 million barrels in the second half of 2020, with transportation and aviation fuels as the main laggards.

Art in War Torn Libya

Libyan digital artist Razan Al Naas (@razangryffindor) weaves the country’s culture and history into digital collages that provoke thought and awe. A large part of that history in recent times has been the instability and conflict that has ravaged the country since the overthrow of longtime dictator Muammar Qaddafi in 2011. 

The increase in fighting since April 2019 upended Tripoli resident Al Naas’ life with her family moving away from their home to escape the constant bombings. The arrival of coronavirus has further interrupted life in the city, closing universities and schools to contain its spread. 

The turmoil of life in Libya is a constant feature of the art produced by many contemporary Libyan artists. Earlier this year, Al Naas repurposed Michaelangelo’s hand of God to show two hands reaching out under a large bottle of hand sanitizer. In the background is Tripoli’s Bab Al Madina. 

The image evokes feelings of hope and hopelessness with the hands ever so close to touching, as in the original, and the hand sanitizer a stark reminder of both the challenges of COVID-19 and the impossibility for many to hold their loved ones at this time.

For Al Naas coronavirus and the associated restrictions to daily life in Libya cannot be disentangled from the war, with the artist telling Arab News in April “In Tripoli, you can’t spell quarantine without war.”

Other works by Al Naas, the majority of which are published on her Instagram, feature dilapidated buildings and faceless soldiers as she continues to document her experiences as a young person living through war. 

Keeping Libya’s art scene alive 

Artists, writers, photographers and poets play a vital role in curating cultural and collective memories of the human experience. The importance of this contribution in Libya was highlighted in a 2017 art show hosted by the WaraQ Art Foundation in the capital. 

At the time, the country’s art scene was beginning to recover after years of conflict, with the exhibition drawing large crowds throughout its five night run. The scars of war were visible throughout the work featured with themes such as the trauma of Islamic State’s barbarism and the impact of the war on children prominent among the art on show. 

Al Naas was among the artists to exhibit in 2017. Her contribution included the piece  “Kidnapped and yet to return.” Drawing on her family’s personal trauma the piece references the kidnapping of her grandfather. The elderly man was held for over a month until the family was able to pay his ransom. 

Al Naas wants the piece to serve as a warning to others, saying “I wanted to share this feeling with everyone. The fact that you could wake up one day to find one of your closest people is kidnapped.” 

Earlier this year, the Tajarrod Art and Architecture Foundation held a three day open air exhibition in Benghazi. Visitors walked among red pillars viewing art produced by young people produced on the exhibitions thematic of building meaning out of destruction.

Whilst COVID-19 has curtailed plans for more exhibitions in the short term and the ongoing conflict makes long term planning difficult, the enthusiasm surrounding art across Libya is an encouraging sign for the industry’s future. 

Is this Self-Cleaning Mask the Future of PPE?

A reusable, rechargeable mask that uses heat to kill traces of the virus could be a game-changer in the COVID-19 personal protection market, Israeli researchers say. 

Many countries around the world have made mask-wearing mandatory in the wake of COVID-19, leading to an uptick in the use and disposal of cheap but unsustainable masks.                                                              

Israeli researchers, concerned about the environmental impact of face-masks, say they have come up with the perfect solution and created a rechargeable mask that uses heat to kill germs and can be used over, and over again. 

Technion University’s lead researcher Professor Yair Ein-Eli says he hopes the new self-cleaning mask will save lives and the environment.  

“The medical world was always  moving towards non-reusable or disposable but when you have a crisis that you need five billion masks in 2020, in 2021 worldwide, five billion, you have to realise that this is not economic or environmentally friendly. Not at all,” Ein-Eli explained.   

“You have to make it reusable and friendly and this is our solution,” the inventor said.  

The prototype looks like a standard N95 face mask but has an in-built layer of carbon fibres that, when plugged in to a USB port, heat to 70 degrees Celsius.  

The heat is enough to kill the virus and disinfect the mask, and is too hot for it to be worn during the 30 minute disinfection process, the research team warns. The freshly disinfected mask is then ready to protect the user from COVID-19 and other airborne diseases.   

The Israeli researchers submitted a US patent in late March, while still in talks with the private sector, expect the auto-cleaning masks will retail at around $1 more than your regular disposable face mask. 

Read also: Cheap Steroid Emerges as Front-runner in COVID-19 Drug Trial 

 

Cheap Steroid Emerges as Front-runner in COVID-19 Drug Trial

Scientists are hailing dexamethasone, a readily-available steroid, as a breakthrough COVID-19 treatment after it was found to cut deaths by one-third in the sickest patients, according to trial results released by Oxford University researchers on June 16.

The drug, used normally as an arthritis treatment, is one of six potential COVID-19 treatments being tested through the Randomised Evaluation of COVID-19 Therapy Trial, known as the “Recovery Trial.” 

On Tuesday, results from a trial conducted by Oxford University’s Nuffield Department of Population Health, showed that dexamethasone reduces the chance of death by up to one-third in the sickest COVID-19 patients 

“It is the only drug so far shown to reduce mortality and it reduces it significantly,” said Oxford University Professor of Emerging Infectious Diseases and study co-lead Peter Horby.  

“It is a major breakthrough, I think,” added an optimistic Horby. 

The Recovery Trial’s other chief investigator, Professor Martin Landray, said that in addition to its lifesaving properties, the drug’s wide availability and low cost were also “immensely important.” 

Landray said the results were so promising that dexamethasone should be added to the COVID-19 treatment regime straight away. 

“This is a (trial) result that shows that if patients who have COVID-19 and are on ventilators or are on oxygen are given dexamethasone, it will save lives, and it will do so at a remarkably low cost,” Landray said in an online briefing about the latest results.  

“It’s going to be very hard for any drug really to replace this, given that for less than 50 pounds ($63.26), you can treat eight patients and save a life,” Landray added. 

The British government has already moved to stockpile 200,000 doses of dexamethasone and will immediately begin using it to treat patients in UK hospitals. Governments around the world will undoubtedly follow suit, and researchers say they are working to publish the trial results quickly given the public health importance of its findings.  

The Recovery Trial has been running since March, and is one of many racing to find effective treatments for COVID-19. In addition to low-dose dexamethasone, the trial assessed the impact of HIV treatment lopinavir-ritonavir, antimalarial hydroxychloroquine, antibiotic azithromycin, anti-inflammatory injection tocilizumab, and plasma from recovered COVID-19 patients as potential disease treatments. 

The researchers randomized a total of 2,104 patients to receive dexamethasone 6 mg once per day for ten days, and compared them with 4,321 patients randomized to receive standard treatment alone. Dexamethasone was found to reduce deaths by one-third in ventilated patients, and by one fifth in other patients receiving oxygen only.

Read also: Latest Drug Trials Find Antimalarials Ineffective Against COVID-19